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Sophora Flavescens Extract

Latin Name: Sophora Flavescen Ait
Appearance: White Crystalline Powder
Used Plant Part: Root
Specification: 1%-98%
Active Ingredients: Sophocarpidine
Test Method: HPLC,UV
Shelf Life: 2 years
Application: Food, Health product addition, Dietary Supplement
Packaging: 1-5kg/Aluminum foil bag ;25kg/Drum or OEM
Certificates: ISO9001: 2015/ISO22000/Halal/Kosher/HACCP

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COA Sophora Extract.pdf
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Product Introduction

What is Sophora Flavescens Extract?

Sophora flavescens, also known as ku shen, is a traditional Chinese medicine that has been used Sophora Flavescens Extract.jpgfor over 2000 years. The extract from the roots of Sophora flavescens contains a variety of bioactive compounds such as matrine, oxymatrine, sophoridine, and formononetin. These compounds give Sophora flavescens extract wide-ranging therapeutic benefits.

It exhibits antiviral, anti-inflammatory, antioxidant, and immunomodulatory properties. The antiviral effects are due to matrine which inhibits viral replication and boosts the immune response against viruses. The anti-inflammatory properties are attributed to oxymatrine which suppresses pro-inflammatory cytokines. It has antioxidant effects because of the presence of polyphenols and flavonoids. It protects cells from oxidative stress and damage. The anticancer effects are due to formononetin which induces cancer cell apoptosis and inhibits angiogenesis. Additionally, Sophora flavescens modulates the immune system by enhancing immune cell proliferation and activity.

COA

Test items and results

Item

Specification

Result

Assay

≥98.0%(HPLC)

98.5%

Physical&Chemical Testing

Appearance

White Crystalline Powder

Conforms

Odor&Taste

Characteristic

Conforms

Sieve Analysis

NLT 95% Through 80 mesh

Conforms

Residue On Ignition

≤5.0%

3.6%

Loss On Drying

≤5.0%

3.8%

PH

9.5-10.5

Conforms

Heavy Metals

≤10ppm

Conforms

Pesticide Residues

≤10ppb

Conforms

Microbiological Testing

Total plate count

≤1000cfu/g

Conforms

Yeast&Mold

≤100cfu/g

Conforms

E.coli

Not detected

Not detected

Salmonella

Not detected

Not detected

Shelf life and Storage

2 Years. Cool & dry place. Keep away from strong light and heat.

Conclusion

Conform to In-house Standard.

Benefits

It has many evidence-based health benefits, making it a valuable medicinal supplement.

Antiviral Effects

Multiple studies have shown sophora flavescens root extract has antiviral activities against a wide range of viruses, including hepatitis B and C, influenza, respiratory syncytial virus, human immunodeficiency virus, and more. The compounds matrine, oxymatrine, and sophoridine inhibit viral entry, replication, assembly, and release from host cells. Sophora extract boosts the immune response against viruses by increasing cytokine production and immunoglobulin levels. The antiviral effects make Sophora extract useful for viral infections like flu, coughs, hepatitis, and diarrhea.

Anti-inflammatory Effects

The compounds in Sophora extract reduce inflammation by inhibiting inflammatory mediators like NF-kB and cytokines such as IL-6, IL-1β, and TNF-α. Oxymatrine specifically decreases inflammation by suppressing iNOS, COX-2, and PGE2. The anti-inflammatory properties make Sophora flavescens useful for inflammatory conditions like arthritis, enteritis, and dermatitis.

Antioxidant Activity

The extract exhibits free radical-scavenging abilities. It increases cellular antioxidant enzymes like superoxide dismutase and glutathione peroxidase. This protects cells from oxidative damage and improves redox homeostasis. The antioxidant effects protect against various oxidative stress-related disorders.

Immunomodulation

The extract regulates the immune system. It stimulates T lymphocytes and macrophages, which enhances the cell-mediated immune response. Sophora extract also increases antibody production by B cells. By boosting immune function, the extract improves the body's resistance against infections and cancer.

Applications

The bioactive compounds in Sophora flavescens extract have made it useful across many industries:

Pharmaceutical Industry: Sophora extract is widely used in prescription drugs and OTC medicines for its antiviral, anticancer, and anti-inflammatory properties. It is formulated into drugs for hepatitis, arthritis, respiratory illnesses, skin diseases, and gastroenteritis.

Nutraceutical Industry:Sophora flavescens is a popular ingredient in dietary supplements and functional foods. Its antioxidant, immune-boosting, and liver-protective effects promote wellness. Sophora supplements help prevent illnesses and enhance health.

Cosmetics Industry: The anti-aging and antimicrobial properties of Sophora extract have led to its use in skincare, haircare, and cosmetic products. It rejuvenates skin, reduces acne, and protects against infections. Sophora is added to creams, serums, cleansers, and lotions.

Food Industry: Sophora extract is used as a natural preservative and flavoring in foods. It inhibits bacterial growth due to its antimicrobial effects. Sophora provides a bitter, floral flavor.

Animal Feed Industry: It has growth-promoting, anti-diarrheal, and immunity-boosting effects in livestock. It is added to animal feed to improve health.

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Quality Assurance

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Packaging

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OEM Services

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Why Choose Wellgreen Technology?

At Wellgreen, we take pride in our commitment to offering the highest quality product. Here's why you should choose us as your supplier:

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Contact Us

If you are a professional buyer or a global distributor looking for high-quality Sophora Flavescens Extract, look no further than Wellgreen. Contact our sales team today to discuss your requirements, request samples, and avail of our competitive pricing. Email: wgt@allwellcn.com.


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